Tulio de Oliveira

Tulio de Oliveira is a Brazilian, Portuguese, and South African permanent resident professor of bioinformatics at the University of KwaZulu-Natal and Stellenbosch University, South Africa, and associate professor of global health at the University of Washington. He has studied outbreaks of chikungunya, dengue, hepatitis B and C, HIV, SARS-CoV-2, yellow fever and Zika. During the COVID-19 pandemic he led the team that confirmed the discovery of the Beta variant of the COVID-19 virus in 2020 and the Omicron variant in 2021.

Tulio de Oliveira
Born
Brazil
Education
AwardsBatho Pele Award (2022)
Scientific career
Institutions

He gained fellowships to Oxford University, Wellcome Trust Sanger Institute, and Edinburgh University, and in 2015 was appointed professor. In 2017, he founded the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) and in 2021 he founded the Centre for Epidemic Response and Innovation (CERI), to sequence and trace epidemics.

Early life

De Oliveira was born in Brazil.[1] He earned a bachelor of science degree from the Federal University of Rio Grande do Sul in Brazil.[2] He completed his MSc and PhD at the Nelson R Mandela School of Medicine, University of KwaZulu-Natal.[2]

Career

During his career he has studied outbreaks of chikungunya, dengue, hepatitis B and C, HIV, SARS-CoV-2, yellow fever and Zika.[2]

From 2004 to 2006 he was a Marie Curie research fellow at Oxford University.[2] In 2015 he was a Newton advanced fellow at the Wellcome Trust Sanger Institute at Edinburgh University and in the same year was appointed professor of bioinformatics at University of KwaZulu-Natal.[1][2] There, in 2017, he founded KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), which has sequenced and traced dengue, Zika, HIV and tuberculosis, in addition to SARS-CoV-2.[1][3] In 2018, the year prior to completing his fellowship at Edinburgh, he was appointed as an associate professor of Global Health at the University of Washington.[2] In July 2021, he became a professor of bioinformatics at Stellenbosch University's School for Data Science and Computational Thinking.[2]

During the COVID-19 pandemic he led the team that confirmed the discovery of the Beta variant of the COVID-19 virus in late 2020.[1][4] He has hypothesised that large groups of previously-infected people with declining immunity directly drive the emergence of variants of concern.[5] If simultaneously there is a high level of transmission, then declining individual immunity may fail to prevent re-infection and if the virus is not cleared in enough people, new dangerous mutations may become more likely, as the virus survives and goes on to infect more people.[5] Subsequently, as principal investigator and leader of the Network for Genomic Surveillance in South Africa, he led the team that confirmed and alerted authorities of the Omicron variant, first sequenced in Johannesburg's Lancet Laboratory, as a new variant in 2021.[4][6][7] After first alerting authorities to the Omicron variant in South Africa, de Oliveira contended that the origin is unknown; he has "insisted that just because it was first detected in South Africa doesn't mean that's where it originated".[8] He reported that it was possible that Omicron came from elsewhere as O. R. Tambo International Airport, Johannesburg, was the largest in Africa.[9]

Recognition and awards

De Oliveira was included in a list of ten scientists with important roles in scientific developments in 2021 compiled by the scientific journal Nature.[1] De Oliveira was included in a list of the leader of genomics surveillance as one of the ten breakthrough technologies in 2022 compiled by the scientific journal MIT_Technology_Review.[10] He received the Gold Medal Award from the South African Medical Research Council (SAMRC) in 2022.[11] In the same year, for his contributions to society, he received the Batho Pele Award from the Government of South Africa.[12]

Selected publications

Articles

  • De Oliveira, T.; Deforche, K.; Cassol, S.; Salminen, M.; Paraskevis, D.; Seebregts, C.; Snoeck, J.; Van Rensburg, E. J.; Wensing, A. M. J.; Van De Vijver, D. A.; Boucher, C. A.; Camacho, R.; Vandamme, A.-M. (1 October 2005). "An automated genotyping system for analysis of HIV-1 and other microbial sequences". Bioinformatics (Oxford, England). 21 (19): 3797–3800. doi:10.1093/bioinformatics/bti607. ISSN 1367-4803. PMID 16076886.
  • Giovanetti, Marta; De Mendonça, Marcos Cesar Lima; Fonseca, Vagner; Mares-Guia, Maria Angélica; Fabri, Allison; Xavier, Joilson; De Jesus, Jaqueline Goes; Gräf, Tiago; Dos Santos Rodrigues, Cintia Damasceno; Dos Santos, Carolina Cardoso; Sampaio, Simone Alves; Chalhoub, Flavia Lowen Levy; De Bruycker Nogueira, Fernanda; Theze, Julien; Romano, Alessandro Pecego Martins; Ramos, Daniel Garkauskas; De Abreu, Andre Luiz; Oliveira, Wanderson Kleber; Do Carmo Said, Rodrigo Fabiano; De Alburque, Carlos F. Campelo; De Oliveira, Tulio; Fernandes, Carlos Augusto; Aguiar, Shirlei Ferreira; Chieppe, Alexandre; Sequeira, Patrícia Carvalho; Faria, Nuno Rodrigues; Cunha, Rivaldo Venâncio; Alcantara, Luiz Carlos Junior; De Filippis, Ana Maria Bispo (12 December 2019). "Yellow Fever Virus Reemergence and Spread in Southeast Brazil, 2016-2019". Journal of Virology. 94 (1): e01623–19. doi:10.1128/JVI.01623-19. ISSN 1098-5514. PMC 6912119. PMID 31597773.
  • Pereira Gusmão Maia, Zuinara; Mota Pereira, Felicidade; Do Carmo Said, Rodrigo Fabiano; Fonseca, Vagner; Gräf, Tiago; De Bruycker Nogueira, Fernanda; Brandão Nardy, Vanessa; Xavier, Joilson; Lima Maia, Maricelia; Abreu, André L.; Campelo De Albuquerque, Carlos F.; Kleber Oliveira, Wanderson; Croda, Julio; De Filippis, Ana Maria Bispo; Venancio Cunha, Rivaldo; Lourenço, Jose; De Oliveira, Tulio; Faria, Nuno Rodrigues; Junior Alcantara, Luiz Carlos; Giovanetti, Marta (2020). "Return of the founder Chikungunya virus to its place of introduction into Brazil is revealed by genomic characterization of exanthematic disease cases". Emerging Microbes & Infections. 9 (1): 53–57. doi:10.1080/22221751.2019.1701954. ISSN 2222-1751. PMC 6968431. PMID 31880218.
  • Wibmer, Constantinos Kurt; Ayres, Frances; Hermanus, Tandile; Madzivhandila, Mashudu; Kgagudi, Prudence; Oosthuysen, Brent; Lambson, Bronwen E.; De Oliveira, Tulio; Vermeulen, Marion; Van Der Berg, Karin; Rossouw, Theresa; Boswell, Michael; Ueckermann, Veronica; Meiring, Susan; von Gottberg, Anne; Cohen, Cheryl; Morris, Lynn; Bhiman, Jinal N.; Moore, Penny L. (2021). "SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma". Nature Medicine. 27 (4): 622–625. bioRxiv 10.1101/2021.01.18.427166. doi:10.1038/s41591-021-01285-x. PMID 33654292. S2CID 232103250.

Books

References

  1. Nordling, Linda (2021). "Nature's 10 Ten people who helped shape science in 2021: A bioinformatician in South Africa helped to identify troubling variants of the coronavirus SARS-CoV-2". Nature. Archived from the original on 22 December 2021. Retrieved 19 December 2021.
  2. "News - Renowned bioinformatician joins forces with..." www.sun.ac.za. 20 July 2021. Archived from the original on 25 December 2021. Retrieved 24 December 2021.
  3. "Tulio de Oliveira | University of Washington - Department of Global Health". globalhealth.washington.edu. University of Washington. Archived from the original on 25 December 2021. Retrieved 24 December 2021.
  4. "How South African Researchers Identified the Omicron Variant of COVID". The New Yorker. 30 November 2021. Archived from the original on 25 December 2021. Retrieved 24 December 2021.
  5. "Part II.A. Deploying the COVID-19 Vaccine in EAP". World Bank East Asia and Pacific Economic Update, Spring 2021: Uneven Recovery. Washington: World Bank Publications. 2021. p. 41. ISBN 978-1-4648-1702-1.
  6. Dyer, Owen (3 December 2021). "Covid-19: South Africa's surge in cases deepens alarm over omicron variant". BMJ. 375: n3013. doi:10.1136/bmj.n3013. ISSN 1756-1833. PMID 34862184. S2CID 244842008. Archived from the original on 30 December 2021.
  7. "How South African scientists discovered Omicron and set off a global chain reaction". ABC17NEWS. C. N. N. 2 December 2021. Retrieved 8 January 2022.
  8. Hurst, Luke (29 November 2021). "Omicron variant poses 'very high' global risk, WHO says". euronews. Archived from the original on 25 December 2021. Retrieved 25 December 2021.
  9. Zubașcu, Florin (2 December 2021). "'Do not blame South Africa' for the Omicron variant". Science|Business. Retrieved 9 January 2022.
  10. Nordling, Linda (2022). "How tracking coronavirus variants will prepare us for the next global public health threat". MIT. Archived from the original on 23 February 2022. Retrieved 2 April 2022.
  11. "SAMRC rolls out the red carpet for leading medical scientists and researchers". www.samrc.ac.za. Archived from the original on 3 April 2022. Retrieved 3 April 2022.
  12. Gumede, Compiled by Nosipho. "UKZN researchers scoop the 2022 National Batho Pele Excellence Awards". Witness. Archived from the original on 2 April 2022. Retrieved 2 April 2022.

Further reading

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