Mehndi Hai Rachne Waali

• Shivangi Khedkar as Pallavi Raghav Rao (formerly Deshmukh) (née Sawant): Raghav's wife; Mandar's former wife; caretaker of Deshmukh Saree Empoium (2021)
• Sai Ketan Rao as Raghav Rao: Pallavi's husband; owner of Jayati Jewels (2021)

• Ashok Phal Dessai as Mandar Deshmukh (alias Raja): Pallavi's vengeful former husband who was presumed dead; Sharda and Vijay's elder son; Devyani's murderer (2021)
• Milind Phatak as Vijay Deshmukh: Pallavi's former father-in-law; Sharda's husband; Mandar and Nikhil's father; owner of Deshmukh Saree Emporium (2021)
  • Sameer Deshpande replaced Milind Phatak (2021)
• Asmita Ajgaonkar as Sharda Deshmukh: Pallavi's former mother-in-law, Vijay's wife, Mandar and Nikhil's mother (2021)
• Karan Manocha as Nikhil Deshmukh: Pallavi's former brother-in-law; Vijay and Sharda's younger son (2021)
• Ajinkya Joshi as Milind Deshmukh: Vijay's younger brother; Sulochana's husband; Mansi and Amruta's father; Pallavi's former uncle-in-law (2021)
• Snehal Reddy as Sulochana Deshmukh: Milind's wife; Mansi and Amruta's mother; Pallavi's former aunt-in-law (2021)
• Rutuja Sawant as Mansi Deshmukh: Milind and Sulochana's elder daughter; Amruta's elder sister, Rahul's ex-fiancée, Pallavi's former cousin sister-in-law (2021)
• Priyanka Dhavale as Amruta Deshmukh: Milind and Sulochana's younger daughter, Mansi's younger sister, Pallavi's former cousin sister-in-law (2021)
• Snehal Borkar as Krishna: Pallavi's friend and assistant at Deshmukh Saree Emporium (2021)
• Ragini Shah as Jaya Rao: Raghav, Kirti and Arjun's mother; Ajit's wife; Pallavi's mother-in-law (2021)
  • Geeta Tyagi replaced Ragini Shah (2021)
• Sayli Salunkhe as Kirti Rao: Raghav's younger sister; Pallavi's friend turned sister-in-law; Sunny's wife (2021)
• Kushagre Dua as Sunny Ahuja: Kirti's husband (2021)[4]
• Himanshu Bamzai as Farhad Nawaz: Raghav's secretary, right-hand man and friend (2021)
• Krishna Kaurav as Harish: Raghav's bodyguard (2021)
• Jeet Pol as Madan: Raghav's bodyguard (2021)
• Shweta Vyas as Esha Madhavan: Raghav’s former girlfriend and obsessed lover (2021)
• Jatin Sharma as Sumit: Esha's estranged husband (2021)
• Sarika Raghwa as Anjali: She tried to get intimate with Raghav despite being engaged to someone else. Later Raghav exposed her in front of her fiancé (2021)
• Saim Khan as Akash: Brother of Pallavi's friend and Kirti's love-interest (2021)
• Gourav Raj Puri as Rahul: Mansi's ex-fiancé; Asha's son (2021)
• Sonal Palan as Asha: Rahul's mother (2021)
• Manoj Kaushik as Siddhesh Sawant: Pallavi's elder brother; Pawani's husband; Raghav's brother-in-law (2021)
• Payal Singh as Pawani Sawant: Siddhesh's wife; Pallavi's sister-in-law; Raghav's sister-in-law (2021)
• Ankit Gulati as Vedant (Ved) aka Lion: Raghav's former best friend and business partner who turned enemy due to business differences (2021)
• Snehal Waghmare as ACP Laxmi Singh: Raghav's enemy (2021)
• Abhay Verma as Rocky: Sunny's friend (2021)
• Ishrat Khan as Dr. Ramya: Mandar/Raja's doctor turn into Amma (2021)
• Supreet Nikam as Vishnu: Mandar/Raja's friend (2021)
• Deepak Soni as Inspector Nitin reddy (2021)

Shivangi Khedkar said, "My character is of a Maharashtrian girl, Pallavi. Since our whole team is Marathi, everyone helps me in speaking words in their language. Even I am working hard on myself".[9]

Based on the backdrop of Hyderabad, the series is mainly filmed at sets in Kolhapur in Maharashtra while some initial sequences were shot in Hyderabad in early February 2021.[10][11]

On 13 April 2021, Chief Minister of Maharashtra, Uddhav Thackeray announced a sudden curfew due to increased COVID-19 cases, while the production halted from 14 April 2021. Soon, the team of the series decided to move their shooting location to Ramoji Film City in Hyderabad until the next hearing.[12] Hence, the production location was shifted temporarily.[13]

It premiered on 15 February 2021 at the 6:30 PM on StarPlus. However, on 11 October 2021, it was shifted to the early-evening slot of 5:30 PM to accommodate upcoming show, Vidrohi.[14][15]

In UK, the series launched with 74.6 thousand viewers being the third most watched Indian television series.[16] On 30 March 2021, it was the most watched series with the viewership of 38.2 thousand .[17] On week ending 12 April 2021, it was the second most watched series with 98.3 thousand viewers.[18] The viewership further increased to 77 thousand on 17 April 2021, being the most watched series.[19] The viewership increased on 25 May 2021 with 89.1 thousand viewers.[20] The viewership then increased more on week ending Sunday 13 June 2021 with 92,400 thousand viewers, it was the second most watched series.[21]

The series went off air on 27 November 2021, after 246 episodes.