COQ3

COQ3, also known as ubiquinone biosynthesis O-methyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ3 gene.

COQ3
Identifiers
Aliases	COQ3, DHHBMT, DHHBMTASE, UG0215E05, bA9819.1, coenzyme Q3, methyltransferase
External IDs	OMIM: 605196 MGI: 101813 HomoloGene: 9683 GeneCards: COQ3
EC number	2.1.1.114
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q16.2 Start 99,369,401 bp[1] End 99,394,195 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 A3|4 9.11 cM Start 21,879,673 bp[2] End 21,912,162 bp[2]
RNA expression pattern Bgee Top expressed in biceps brachii deltoid muscle myocardium right ventricle left ventricle muscle of leg vastus lateralis muscle quadriceps femoris muscle heart More reference expression data BioGPS n/a
Gene ontology Molecular function methyltransferase activity transferase activity hexaprenyldihydroxybenzoate methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity O-methyltransferase activity 3-demethylubiquinone-9 3-O-methyltransferase activity decaprenyldihydroxybenzoate methyltransferase activity 3-demethylubiquinol-10 3-O-methyltransferase activity GO:0001948 protein binding Cellular component mitochondrial inner membrane mitochondrial matrix mitochondrion membrane extrinsic component of mitochondrial inner membrane Biological process methylation ubiquinone biosynthetic process glycerol metabolic process regulation of ubiquinone biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51805	230027
Ensembl	ENSG00000132423	ENSMUSG00000028247
UniProt	Q9NZJ6	Q8BMS4
RefSeq (mRNA)	NM_017421	NM_172687 NM_001356348
RefSeq (protein)	NP_059117	NP_766275 NP_001343277
Location (UCSC)	Chr 6: 99.37 – 99.39 Mb	Chr 4: 21.88 – 21.91 Mb
PubMed search	[3]	[4]
Wikidata
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