Rhc80267

RHC80267 is an inhibitor of diacylglycerol lipase.[1] Diacylglycerol lipase generates the endocannabinoid 2-arachidonoylglycerol from diacylglycerol.

Rhc80267
Names
Preferred IUPAC name
N′,N′′′-(Hexane-1,6-diyl)bis(N-cyclohexylidenehydroxylamine-O-carboxamide)
Other names
RHC 80267, RG 80267, U 57908
Identifiers
3D model (JSmol)
ChemSpider
MeSH 1,6-bis(cyclohexyloximinocarbonyl)hexane
UNII
  • InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26) N
    Key: RXSVYGIGWRDVQC-UHFFFAOYSA-N N
  • C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
Properties
C20H34N4O4
Molar mass 394.26
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

References
  1. Sutherland CA, Amin D (1982). "Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267". J. Biol. Chem. 257 (23): 14006–10. PMID 7142192.
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