Hélène Bergès

Hélène Bergès (born August 27, 1966 in Pau) is a French scientist and was the Director of the French Plant Genomic Resources Center from its foundation until 2019.

Hélène Bergès
Born (1966-08-27) 27 August 1966
Pau, France
NationalityFrench
Alma materUniversity of Toulouse III
Awards
  • IWGSC Leadership Award (2019)
  • Vermeil Medal of French Academy of Agriculture (2015)
  • Legion of Honor (2015)
  • Order of Agricultural Merit (2013)
Scientific career
FieldsGenomics
ThesisEtude de l'export de protéïnes hétérologues chez la bactérie Escherichia coli (1995)

Education

Bergès completed a doctorate in 1995 at the Toulouse III - Paul Sabatier University in the fields of genetics and molecular biology.[1]

Career

After her PhD, Bergès joined the National Institute for Agricultural Research (INRA) in 1998, to first focus on research in studying plant interactions with microbes. In 2003, her position at INRA allowed her to found a separate department called the French Plant Genomic Resources Center (CNRGV) where she was the director until 2019.[1] Employing some twenty people, the CNRGV is involved in various international sequencing consortia, develops various projects funded by the French Government (Grand Emprunt), the French National Research Agency (ANR) or the European Union, in collaboration with various laboratories all around the world. Along other activities, Hélène Bergès is member of the scientific committee of the Parliamentary Office for the Evaluation of Scientific and Technological Options (OPECST).[1] In 2021, she was one of the researchers highlighted in the " La Science taille XX elles" exhibition presented in Toulouse.[2]

Research

Bergès' early research used Escherichia coli as a model system to examine cytokines[3] and plasmid copy numbers.[4] She then she moved on to examine the bacterial cells associated with plant roots including the development of microarrays[5] which allowed her to quantify gene expression in these bacteria.[6][7] She was an early adopter of the need to sequence plant genomes,[8] and her recent work includes large-scale sequencing projects including those generating genomic information on barley,[9] wheat,[10] and sunflowers.[11]

Selected publications
  • "A physical, genetic and functional sequence assembly of the barley genome". Nature. 491 (7426): 711–716. November 2012. doi:10.1038/nature11543.
  • Becker, Anke; Bergès, Hélène; Krol, Elizaveta; Bruand, Claude; Rüberg, Silvia; Capela, Delphine; Lauber, Emmanuelle; Meilhoc, Eliane; Ampe, Frédéric; de Bruijn, Frans J.; Fourment, Joëlle; Francez-Charlot, Anne; Kahn, Daniel; Küster, Helge; Liebe, Carine; Pühler, Alfred; Weidner, Stefan; Batut, Jacques (1 March 2004). "Global Changes in Gene Expression in Sinorhizobium meliloti 1021 under Microoxic and Symbiotic Conditions". Molecular Plant-Microbe Interactions. 17 (3): 292–303. doi:10.1094/MPMI.2004.17.3.292. ISSN 0894-0282.
  • Young, Nevin D.; Debellé, Frédéric; Oldroyd, Giles E. D.; Geurts, Rene; Cannon, Steven B.; Udvardi, Michael K.; et al. (December 2011). "The Medicago genome provides insight into the evolution of rhizobial symbioses". Nature. 480 (7378): 520–524. doi:10.1038/nature10625.
  • Yousfi, Fatma-Ezzahra; Makhloufi, Emna; Marande, William; Ghorbel, Abdel W.; Bouzayen, Mondher; Bergès, Hélène (31 January 2017). "Comparative Analysis of WRKY Genes Potentially Involved in Salt Stress Responses in Triticum turgidum L. ssp. durum". Frontiers in Plant Science. 7. doi:10.3389/fpls.2016.02034.
  • Bergès, Hélène; Lauber, Emmanuelle; Liebe, Carine; Batut, Jacques; Kahn, Daniel; Bruijn, Frans J. de; Ampe, Frédéric (2003). "Development of Sinorhizobium meliloti Pilot Macroarrays for Transcriptome Analysis". Applied and Environmental Microbiology. doi:10.1128/AEM.69.2.1214-1219.2003.
  • Bergès, Hélène; Checroun, Claire; Guiral, Sébastien; Garnerone, Anne-Marie; Boistard, Pierre; Batut, Jacques (2001). "A glutamine-amidotransferase-like protein modulates FixT anti-kinase activity in Sinorhizobium meliloti". BMC Microbiology. 1 (1): 6. doi:10.1186/1471-2180-1-6.
  • Bergès, H; Oreglia, J; Joseph-Liauzun, E; Fayet, O (February 1997). "Isolation and characterization of a priB mutant of Escherichia coli influencing plasmid copy number of delta rop ColE1-type plasmids". Journal of Bacteriology. 179 (3): 956–958. doi:10.1128/jb.179.3.956-958.1997.

Awards and honors

The National Institute for Agricultural Research gave Bergès their 2012 engineering award.[12] She was one of ten recipients of the 2015 Vermeil Medal of the French Academy of Agriculture,[13] and she was given the 2018 "Outstanding Leadership Award" from the International Wheat Genome Sequencing Consortium, for "her leadership in BAC pooling and BAC libraries".[14] In 2015, she was made Knight of Legion of Honour,[15] and she is also a Knight of the Order of Agricultural Merit.

References
  1. "Helene Bergès: Genomicist". cnrs.fr. French National Centre for Scientific Research. 2021. Retrieved January 8, 2022.
  2. "Hélène Bergès | CNRS". www.cnrs.fr (in French). November 17, 2021. Retrieved 2022-01-08.{{cite web}}: CS1 maint: url-status (link)
  3. Bergès, H; Joseph-Liauzun, E; Fayet, O (January 1996). "Combined effects of the signal sequence and the major chaperone proteins on the export of human cytokines in Escherichia coli". Applied and Environmental Microbiology. 62 (1): 55–60. doi:10.1128/aem.62.1.55-60.1996.
  4. Bergès, H; Oreglia, J; Joseph-Liauzun, E; Fayet, O (February 1997). "Isolation and characterization of a priB mutant of Escherichia coli influencing plasmid copy number of delta rop ColE1-type plasmids". Journal of Bacteriology. 179 (3): 956–958. doi:10.1128/jb.179.3.956-958.1997.
  5. Bergès, Hélène; Lauber, Emmanuelle; Liebe, Carine; Batut, Jacques; Kahn, Daniel; Bruijn, Frans J. de; Ampe, Frédéric (2003). "Development of Sinorhizobium meliloti Pilot Macroarrays for Transcriptome Analysis". Applied and Environmental Microbiology. doi:10.1128/AEM.69.2.1214-1219.2003.
  6. Becker, Anke; Bergès, Hélène; Krol, Elizaveta; Bruand, Claude; Rüberg, Silvia; Capela, Delphine; et al. (1 March 2004). "Global Changes in Gene Expression in Sinorhizobium meliloti 1021 under Microoxic and Symbiotic Conditions". Molecular Plant-Microbe Interactions. 17 (3): 292–303. doi:10.1094/MPMI.2004.17.3.292. ISSN 0894-0282.
  7. Bergès, Hélène; Checroun, Claire; Guiral, Sébastien; Garnerone, Anne-Marie; Boistard, Pierre; Batut, Jacques (2001). "A glutamine-amidotransferase-like protein modulates FixT anti-kinase activity in Sinorhizobium meliloti". BMC Microbiology. 1 (1): 6. doi:10.1186/1471-2180-1-6.
  8. "Toulouse. Guérir des maladies grâce à l'ADN de la tomate". ladepeche.fr (in French). October 4, 2012. Retrieved 2022-01-08.{{cite web}}: CS1 maint: url-status (link)
  9. "A physical, genetic and functional sequence assembly of the barley genome". Nature. 491 (7426): 711–716. November 2012. doi:10.1038/nature11543.
  10. Paux, Etienne; Sourdille, Pierre; Salse, Jérôme; Saintenac, Cyrille; Choulet, Frédéric; Leroy, Philippe; et al. (3 October 2008). "A Physical Map of the 1-Gigabase Bread Wheat Chromosome 3B". Science. doi:10.1126/science.1161847.
  11. Badouin, Hélène; Gouzy, Jérôme; Grassa, Christopher J.; Murat, Florent; Staton, S. Evan; Cottret, Ludovic; et al. (June 2017). "The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution". Nature. 546 (7656): 148–152. doi:10.1038/nature22380.
  12. "Hélène Bergès, le génome de sa vie" [Hélène Bergès, the genome of her life]. echosciences-sud.fr (in French). Echosciences Occitanie. January 29, 2018. Retrieved January 8, 2022.
  13. "Médaille de VERMEIL de l'Académie". academie-agriculture.fr. French Academy of Agriculture. 2015. Retrieved January 8, 2022.
  14. "Hélène Bergès". 2018 Awardees. International Wheat Genome Sequencing Consortium. February 8, 2019.
  15. "Légion d'honneur : Pierre Soulages grand croix, Sinclair et Bel chevaliers, Enders commandeur" [Legion of Honor: Pierre Soulages Grand Croix, Sinclair and Bel Chevaliers, Enders Commander]. La Dépêche du Midi (in French). June 4, 2015. Retrieved January 8, 2022.

Further reading
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