CACUL1
CDK2 associated cullin domain 1 is a protein that in humans is encoded by the CACUL1 gene. [5]
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| Aliases | CACUL1, C10orf46, CAC1, CDK2 associated cullin domain 1 | ||||||||||||||||||||||||
| External IDs | MGI: 1926082 HomoloGene: 17821 GeneCards: CACUL1 | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr 10: 118.67 – 118.76 Mb | Chr 19: 60.51 – 60.57 Mb | |||||||||||||||||||||||
| PubMed search | [3] | [4] | |||||||||||||||||||||||
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References
- GRCh38: Ensembl release 89: ENSG00000151893 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000033417 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: CDK2 associated cullin domain 1". Retrieved 2018-01-05.
Further reading
- Kong Y, Nan K, Yin Y (2009). "Identification and characterization of CAC1 as a novel CDK2-associated cullin". Cell Cycle. 8 (21): 3552–61. doi:10.4161/cc.8.21.9955. PMID 19829063.
- Kong Y, Bai PS, Sun H, Nan KJ (2012). "Expression of the newly identified gene CAC1 in the hippocampus of Alzheimer's disease patients". J. Mol. Neurosci. 47 (2): 207–18. doi:10.1007/s12031-012-9717-5. PMID 22415352. S2CID 14719772.
- Kong Y, Bai PS, Sun H, Nan KJ, Chen NZ, Qi XG (2012). "The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer". Int. J. Biochem. Cell Biol. 44 (12): 2321–32. doi:10.1016/j.biocel.2012.08.006. PMID 22903020.
- Moon M, Um SJ, Kim EJ (2012). "CAC1 negatively regulates RARα activity through cooperation with HDAC". Biochem. Biophys. Res. Commun. 427 (1): 41–6. doi:10.1016/j.bbrc.2012.08.142. PMID 22982681.
- Kim J, Park UH, Moon M, Um SJ, Kim EJ (2013). "Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1". FEBS Lett. 587 (1): 17–22. doi:10.1016/j.febslet.2012.10.054. PMID 23178685. S2CID 207659623.
- Zheng Q, Zhao LY, Kong Y, Nan KJ, Yao Y, Liao ZJ (2013). "CDK-associated Cullin 1 can promote cell proliferation and inhibit cisplatin-induced apoptosis in the AGS gastric cancer cell line". World J Surg Oncol. 11: 5. doi:10.1186/1477-7819-11-5. PMC 3585504. PMID 23311997.
- Chen TJ, Gao F, Yang T, Thakur A, Ren H, Li Y, Zhang S, Wang T, Chen MW (2013). "CDK-associated Cullin 1 promotes cell proliferation with activation of ERK1/2 in human lung cancer A549 cells". Biochem. Biophys. Res. Commun. 437 (1): 108–13. doi:10.1016/j.bbrc.2013.06.048. PMID 23806693.
- Kong Y, Ma LQ, Bai PS, Da R, Sun H, Qi XG, Ma JQ, Zhao RM, Chen NZ, Nan KJ (2013). "Helicobacter pylori promotes invasion and metastasis of gastric cancer cells through activation of AP-1 and up-regulation of CACUL1". Int. J. Biochem. Cell Biol. 45 (11): 2666–78. doi:10.1016/j.biocel.2013.08.015. PMID 24004834.
- Ma HL, Wen XP, Zhang XZ, Wang XL, Zhao DL, Che SM, Dang CX (2015). "miR-106a* inhibits the proliferation of esophageal carcinoma cells by targeting CDK2-associated Cullin 1 (CACUL1)". Cell. Mol. Biol. (Noisy-le-grand). 61 (4): 56–62. PMID 26314198.
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