4-Acetoxy-MET

4-Acetoxy-MET (4-Acetoxy-N-methyl-N-ethyltryptamine), also known as metacetin or 4-AcO-MET, is a hallucinogenic tryptamine. It is the acetate ester of 4-HO-MET, and a homologue of 4-AcO-DMT. It is a novel compound with very little history of human use. It is sometimes sold as a research chemical by online retailers.

4-Acetoxy-MET
Names
Preferred IUPAC name
3-{2-[Ethyl(methyl)amino]ethyl}-1H-indol-4-yl acetate
Other names
4-Acetoxy-MET; Metacetin; 4-Acetoxy-N-methyl-N-ethyltryptamine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C15H20N2O2/c1-4-17(3)9-8-12-10-16-13-6-5-7-14(15(12)13)19-11(2)18/h5-7,10,16H,4,8-9H2,1-3H3
    Key: OMDKHOOGGJRLLX-UHFFFAOYSA-N
  • InChI=1/C15H20N2O2/c1-4-17(3)9-8-12-10-16-13-6-5-7-14(15(12)13)19-11(2)18/h5-7,10,16H,4,8-9H2,1-3H3
    Key: OMDKHOOGGJRLLX-UHFFFAOYAM
  • CCN(C)CCc1c[nH]c2c1c(ccc2)OC(=O)C
Properties
C15H20N2O2
Molar mass 260.337 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

It is expected that the compound is quickly hydrolyzed into the free phenolic 4-HO-MET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking.

Legality

4-Acetoxy-MET is unscheduled in the United States. It may be considered an analogue of Psilocin, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical purposes could be considered a crime under the Federal Analogue Act

4-Acetoxy-MET is a controlled substance in Switzerland under Verzeichnis E [1]

4-Acetoxy-MET is a Class A drug in the UK because it is an ester of the drug 4-HO-MET, which is a Class A drug under the tryptamine catch-all clause[2]

References

  1. "Fedlex". www.fedlex.admin.ch. Retrieved 2021-08-15.
  2. "Misuse of Drugs Act 1971". 2021-08-15. Archived from the original on 2012-11-11.



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